How is the dose rate defined for medium-dose rate (MDR) treatments?

The definition of medium-dose rate (MDR) treatments is characterized by a dose rate that falls within a specific range where biological response to the radiation can be somewhat controlled, allowing for a balance between effectiveness and minimizing damage to surrounding healthy tissues. The range of 2 to 12 Gy per hour exemplifies this, as it indicates an intermediate level of intensity and aggressiveness in the radiation therapy administered.

This range is particularly relevant in brachytherapy and other forms of radiation treatment where the dose rate affects the therapeutic ratio, emphasizing the need for precision when delivering treatments. Treatments falling into this category can exploit the radiobiological effects more effectively compared to low-dose rate or high-dose rate treatments. Thus, understanding that medium-dose rate encompasses doses of 2 to 12 Gy per hour is vital for dosimetry planning and ensures that practitioners can achieve optimal outcomes for patients.