According to ICRU 50, what is the desired dose uniformity in the PTV?

In the context of the ICRU 50 guidelines, the desired dose uniformity within the Planning Target Volume (PTV) is specified as ±5%. This guideline emphasizes the importance of delivering a consistent and homogenous dose to the target area while minimizing the variation in doses received by surrounding healthy tissues.

Maintaining a uniform dose is critical in radiation therapy as it helps ensure that the tumor receives an adequate dose for effective treatment, while also reducing the risk of complications associated with high doses to nearby healthy structures. The ±5% standard is designed to provide a balance between treatment effectiveness and safety, making it an essential benchmark for medical dosimetrists when planning and evaluating treatment modalities.

While the other options suggest different uniformity ranges, they do not conform to the ICRU 50 recommendation, which explicitly states the critical nature of achieving this level of uniformity for optimal therapeutic outcomes.